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LSD

LSD (Lysergic Acid Diethylamide) is a powerful psychedelic compound first synthesized in 1938 by Swiss chemist Albert Hofmann. Known for its profound effects on perception, thought, and consciousness, LSD can induce altered states that include visual hallucinations, expanded awareness, and deep introspection. It became a cultural symbol of the counterculture movement of the 1960s and continues to be studied for its potential therapeutic and spiritual applications.

Origins & Background

  • Discovery: Albert Hofmann synthesized LSD at Sandoz Laboratories while researching ergot alkaloids. He famously experienced its effects in 1943, an event later called Bicycle Day.
  • Cultural role: LSD influenced art, music, and spirituality in the 1960s, embraced by figures such as Timothy Leary, Ram Dass, and the Beat poets.
  • Scientific research: Before prohibition, LSD was studied for its potential to treat depression, alcoholism, and trauma. Today, research is resurging in the field of psychedelic-assisted therapy.
  • Meaning in Context

    LSD is often called a “consciousness-expanding” substance rather than just a hallucinogen. It opens doors to new perceptions of self and reality, sometimes described as mystical or transformative. In my work, references to LSD point less to recreational use and more to its archetypal role: a mirror of the psyche that can reveal hidden patterns, dissolve ego boundaries, and remind us of the vastness of mind.

    Applications & Benefits

    • Therapeutic potential: Recent studies show promise for treating depression, anxiety, and addiction.
    • Spiritual exploration: Can induce mystical-type experiences of unity and transcendence.
    • Creativity and insight: Historically used by artists and thinkers to expand imagination.
    • Psychological growth: Confronts the subconscious, making hidden material visible.

    (Note: LSD remains a controlled substance in most countries. Safety, legality, and guidance are essential considerations.)

    Related Teachings & Lineages

    Antoine'S NOTES

    Semantic Keywords

    FAQ

    What does LSD do?

    It alters perception, mood, and cognition, often producing visual hallucinations, time distortion, and profound insights.

    LIBRARY

    Fear and Loathing in Las Vegas
    A Savage Journey to the Heart of the American Dream
    Fear and Loathing in Las Vegas is the best chronicle of drug-soaked, addle-brained, rollicking good times ever committed to the printed page. It is also the tale of a long weekend road trip that has gone down in the annals of American pop culture as one of the strangest journeys ever undertaken.
    The Electric Kool-Aid Acid Test
    Tom Wolfe's genre-defining magical mystery tour through the 1960s published in Vintage Classics for the first time to mark its fiftieth anniversary.WITH AN INTRODUCTION BY JARVIS COCKERIn the summer of 1964, author Ken Kesey and his Merry Band of Pranksters set out on an awesome social experiment like no other. Blazing across America in their day-glo schoolbus, doped up and deep ‘in the pudding’, the Pranksters’ arrival on the scene – anarchic, exuberant and LSD-infused – would turn on an entire counter-culture, and provide Tom Wolfe with the perfect free-wheeling subject for this, his pioneering masterpiece of New Journalism.' The Electric Kool-Aid Acid Test is not simply the best book on the hippies, it is the essential book...the pushing, ballooning heart of the matter' New York Times
    The Psychedelic Experience
    A Manual Based on the Tibetan Book of the Dead
    This manual uses material from The Tibetan Book of the Dead for this preparation. The authors also make an important contribution to the interpretation of The Tibetan Book of the Dead. They show that it is concerned not with the dead, but with the living. The last section of the manual provides instructions for an actual psychedelic session, under adequate safeguards.

    The authors were engaged in a program of experiments with LSD and other psychedelic drugs at Harvard University until sensational national publicity unfairly concentrating on student interest in the drugs, led to the suspension of the experiments. Since then, the authors have continued their work without academic auspices.
    How to Change Your Mind
    The New Science of Psychedelics
    Could psychedelic drugs change our worldview? One of America's most admired writers takes us on a mind-altering journey to the frontiers of human consciousness

    When LSD was first discovered in the 1940s, it seemed to researchers, scientists and doctors as if the world might be on the cusp of psychological revolution. It promised to shed light on the deep mysteries of consciousness, as well as offer relief to addicts and the mentally ill. But in the 1960s, with the vicious backlash against the counter-culture, all further research was banned. In recent years, however, work has quietly begun again on the amazing potential of LSD, psilocybin and DMT. Could these drugs in fact improve the lives of many people? Diving deep into this extraordinary world and putting himself forward as a guinea-pig, Michael Pollan has written a remarkable history of psychedelics and a compelling portrait of the new generation of scientists fascinated by the implications of these drugs. How to Change Your Mind is a report from what could very well be the future of human consciousness.
    LSD: A Journey into the Asked, the Answered, and the Unknown
    Out of print for more than half a century, A Journey into the Asked, the Answered, and the Unknown , is now available in a commemorative edition, with candid commentary, a new introduction by counterculture journalist Jessica Hundley, and a photographic portrait of a generation. 

    In the midst of a raging national controversy around the indiscriminate use of LSD, two authorities – Richard Alpert, PhD (AKA Ram Dass) and psychoanalyst Sidney Cohen, MD – spoke out on the dangers, merits, legal regulations and control of the revolutionary psychedelic drug. Their book was illustrated with a groundbreaking photo essay by journalist Lawrence Schiller , whose cover story for Life magazine introduced America to the sweeping new LSD epidemic and was a precursor to the federal criminalization of the drug. As the first national photojournalist to capture the American acid scene from the inside, Schiller began with a single contact in Berkeley, California, and built a large network of young, receptive subjects who allowed him to document their private experiences with LSD. At first, his contacts were few and difficult. “Many of them were afraid,” and said no. There were others, however, who were trying to exercise their rebellion, “and some…had a sort of missionary quality. They not only wanted to tell about their experiences; they seemed as though they had to.” Schiller’s reporting expanded to include Timothy Leary , then on trial in Laredo, Texas, and the Merry Pranksters , who stopped by his studio for stroboscopic photos after the Hollywood Acid Test. 

    The deeper he went into the story, the more questions he had. Questions like, “Is the LSD state reality or illusion?” and “Can you understand…without having had “the experience?” Figuring others did as well, he asked Alpert and Cohen to answer them for readers—from their two opposing points of view. The unexpected result is perhaps one of the most deeply informative documents on psychedelics ever published. It sold close to a million copies. At a time when the use of consciousness-expanding substances is again making headlines, the moment that LSD burst out from the rarified world of Timothy Leary and Richard Alpert’s experiments at Harvard to acid parties on the Sunset Strip is worth a second look. 
    Food Of The Gods
    A Radical History of Plants, Psychedelics and Human Evolution
    Food of the Gods explores the idea that psychoactive plants played a central role in shaping human consciousness, culture, language, religion, and creativity. McKenna argues that early humans encountered visionary plants such as psilocybin mushrooms, which acted as catalysts for neural expansion, perception shifts, symbolic thinking, and the mystical impulse.

    The book proposes psychedelics as ancient tools of initiation — dissolving the ego, revealing the deeper field of awareness, and opening access to archetypes of death, rebirth, and divine communion.

    Rather than portraying these substances as escapes, McKenna frames them as technologies of evolution — part of the human dialogue with nature and the invisible world.

    Meet people related to

    LSD

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